International journal of surgery (London, England)
A noninvasive AI model based on multi-dimensional MRI features for predicting tertiary lymphoid structures, immunotherapy response, and prognosis in rectal cancer.
Huancheng Yang, Chinting Wong, Weiye Liang, Peiyi Xie, Gengjia Chen, Decai Ma, Weisen Liu, Xiaobin Xie, Zaiyi Liu, Huimao Zhang, Yu Fu, Xiaochun Meng
Published: 202510.1097/JS9.0000000000003845
Abstract
BACKGROUND: Tertiary lymphoid structures (TLSs) in rectal cancer (RC) are closely associated with immunotherapy response and patient prognosis, yet their assessment currently relies on invasive biopsy. This study aimed to investigate whether TLSs can…
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