Journal of clinical psychopharmacologyHumansClozapineMaleFemaleAdult
Fatal Outcomes in Use of Clozapine: A VigiBase Study of 6402 Women and 11,222 Men.
Carlos De Las Cuevas, Emilio J Sanz, Jose de Leon
Published: 202510.1097/JCP.0000000000002088
Abstract
PURPOSE/BACKGROUND: In 1975, US clozapine studies stopped after pharmacovigilance identified 8 Finnish fatal outcomes during agranulocytosis. In 1989, clozapine was approved with hematological monitoring for treatment-resistant schizophrenia. This st…
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