Therapeutic drug monitoring
Development and Validation of a Simultaneous Quantification Method for 12 Targeted Therapies and 3 Active Metabolites in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry: An Application to Therapeutic Drug Monitoring in Patients With Hematological Malignancies.
Nicolas Vignal, Marie Allard, Sofiane Fodil, Etienne Lengline, Hélène Sauvageon, Marie Sébert, Alain Plé, Delphine Rea, Samia Mourah, Lauriane Goldwirt
Published: 202510.1097/FTD.0000000000001426
Abstract
BACKGROUND: Treatment strategies for hematological cancers and immunological diseases increasingly incorporate targeted oral therapies. These drugs provide improved quality of life but exhibit complex pharmacokinetics. Therapeutic drug monitoring (TD…
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