Epidemiology (Cambridge, Mass.)HumansVaccine EfficacyConfounding FactorsEpidemiologicOdds Ratio
Identification and Estimation of Vaccine Effectiveness in the Test-Negative Design Under Equi-confounding.
Christopher B Boyer, Kendrick Qijun Li, Xu Shi, Eric J Tchetgen Tchetgen
Published: 202610.1097/EDE.0000000000001926
Abstract
The test-negative design (TND) is widely used to evaluate vaccine effectiveness in real-world settings. In a TND study, individuals with similar symptoms who seek care are tested, and effectiveness is estimated by comparing vaccination histories of t…
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