Chinese medical journal
Untargeted metabolomics based on LC-MS and GC-MS reveal metabolic reprogramming and putative biomarkers in amyotrophic lateral sclerosis.
Xiaojiao Xu, Qinming Zhou, Xiaojie Zhang, Tianbai Li, Long Niu, Guowang Xu, Sheng Chen, Yaping Shao, Weidong Le
Published: 202510.1097/CM9.0000000000003874
Abstract
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with unknown etiology. The absence of reliable biochemical and imaging markers often delays diagnosis and limits treatment effectiveness. As metabolic reprogramming…
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