Chinese medical journal
A cigarette compound-induced tumor microenvironment promotes sorafenib resistance in hepatocellular carcinoma via the 14-3-3η-modified tumor-associated proteome.
Ming Jin, Xinru Du, Na Dong, Zhihui Feng, Yuanze Sun, Sisi Song, Hongquan Zhang, Maoxuan Li, Shuoke Duan, Ming Lu, Qinliang Mo, Chi Zhang, Dong Xue, Xiaojun Yang, Chengwu Tang
Published: 202510.1097/CM9.0000000000003851
Abstract
BACKGROUND: Sorafenib resistance is the bottleneck in the clinical treatment of advanced hepatocellular carcinoma (HCC). Cigarette compounds accelerate HCC progression and chemotherapy resistance by forming a chemical microenvironment. Here, we aimed…
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