Anesthesiology
Evaluating the Acute Effects of the Cannabinoid Dronabinol and the Opioid Hydromorphone Alone and in Combination: A Double-Blind, Randomized, Placebo-Controlled Trial in Knee Osteoarthritis.
Katrina R Hamilton, Chung Jung Mun, Eliot Sadik, Cecilia L Bergeria, Andrew S Huhn, Traci J Speed, Ryan Vandrey, Kelly E Dunn, Claudia M Campbell
Published: 202510.1097/ALN.0000000000005925
Abstract
BACKGROUND: This within-subject, double-blind, randomized, placebo-controlled study aimed to determine the acute analgesic and drug effects, and risk for extramedical use, of synthetic delta-9-tetrahydrocannabinol and hydromorphone, alone and in comb…
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