Anesthesiology
Modulation of pain sensitivity by the locus coeruleus-paraventricular thalamic nucleus-anterior cingulate cortex pathway in mice.
Shihui Kuai, Zijie Li, Ziyi Wu, Yongda Liu, Xuejiao Wang, Xueru Wang, Kaiwen Tang, Nanjue Cao, Shiyue Fan, Xu Yang, Pingting Yang, Ling Qin, Ping Zhao
Published: 202510.1097/ALN.0000000000005897
Abstract
BACKGROUND: Noradrenergic projections from the locus coeruleus (LC) to the thalamus and anterior cingulate cortex (ACC) contribute to pain‒like behaviors, yet their hierarchical organization remains unclear. Here, we examined how LC‒derived norepinep…
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