Anesthesiology
Effects of γ-Aminobutyric Acid and Glutamate Signalings from Primary Sensory Neurons to Gate the Spinal Transmission of Mechanical Pain in Mice.
Shu-Jin Wu, Hu-Hu Bai, Yan-Ni Liu, Qi Zhang, Yu-Bo Gao, Juan Li, Xu Yang, Jia-Ning Dang, Xiao-Xue Liu, Xue Bai, Xian Yang, Zhan-Wei Suo, Xiao-Dong Hu
Published: 202610.1097/ALN.0000000000005854
Abstract
BACKGROUND: The majority of dorsal root ganglion neurons are excitatory glutamatergic neurons. Recent studies suggest that a subset of dorsal root ganglion neurons are able to synthesize γ-aminobutyric acid (GABA) and are immunoreactive to vesicular…
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