Journal of addiction medicine
Complicating Factors Surrounding Concurrent Use of Kratom and a Novel 7-hydroxymitragynine Product Among a Participant Enrolled in a Kratom Clinical Trial.
Kirsten E Smith, Siva Rama Raju Kanumuri, Abhisheak Sharma, Rachel Rattenni, Robert LeComte, Christopher R McCurdy, Edward W Boyer, Eric C Strain
Published: 202510.1097/ADM.0000000000001604
Abstract
BACKGROUND: 7-Hydroxymitragynine (7-OH) is a highly selective mu opioid receptor agonist with binding affinity greater than morphine. Although trace amounts of 7-OH are found in kratom, it is formed by metabolism in humans after kratom ingestion. Nov…
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