FASEB journal : official publication of the Federation of American Societies for Experimental BiologyHumansPregnancyTrophoblastsDiabetesGestational
Differential Activation of p53-Lamin A/C and p16-Rb-Mediated Senescence Pathways in Trophoblasts From Pregnancies Complicated by Type A2 Gestational Diabetes Mellitus.
Leena Kadam, Kaylee Chan, Kylia Ahuna, Nicole E Marshall, Leslie Myatt
Published: 202610.1096/fj.202503771RR
Abstract
Gestational diabetes mellitus (GDM) increases the risks for fetal complications such as large-for-gestational-age infants and stillbirth, and disposes both the mother and fetus to develop type 2 diabetes in later life. The placenta, which is crucial…
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