FASEB journal : official publication of the Federation of American Societies for Experimental BiologyHumansMendelian Randomization AnalysisOsteoarthritisT-LymphocytesSingle-Cell Analysis
Mining Potential Therapeutic Targets for T Cell Exhaustion in Osteoarthritis by Integrating Mendelian Randomization and Single-Cell Sequencing.
Jiahong Li, Yi Ye, Yan Zhang, Wei Fang, Fei Lan, Qian Yang, Lun Wan, Jiang Hu, Chengwei Xiao, Kun Zhang
Published: 202610.1096/fj.202503295R
Abstract
Studies have shown that T cell exhaustion (TEX) indirectly influences the onset and progression of osteoarthritis (OA). This study aimed to ascertain biomarkers associated with TEX-related genes (TEXRGs) in OA, offering potential targets for therapy…
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