FASEB journal : official publication of the Federation of American Societies for Experimental BiologyHumansLeukemiaMyeloidAcuteDrug Resistance
CRTC2 Promotes AML Progression and Mediates Mitochondrially-Driven Venetoclax Resistance.
Xiaomei Liang, Yilu Zheng, Bangxue Jiang, Yuling Huang, Jing Tang, Haimei Deng, Chenxing Zhang, Minyi Zhao, Dongjun Lin
Published: 202510.1096/fj.202503054R
Abstract
Acute myeloid leukemia (AML) is a hematologic malignancy characterized by the malignant proliferation of myeloid progenitor cells. Although the introduction of the B-cell lymphoma-2 (BCL-2) inhibitor Venetoclax (VEN) has significantly improved patien…
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