FASEB journal : official publication of the Federation of American Societies for Experimental BiologyNeoplasm ProteinsHepatocyte Nuclear Factor 3-alphaLipid DropletsAnoikisAdenocarcinoma of Lung
FOXA1 Upregulates HILPDA to Enhance Lipid Droplet Accumulation and Anoikis Resistance in Lung Adenocarcinoma.
Sheng Fan, Bingqiang Cai, Daqiang Xu, Yuan He, Hui Lin, Xiuyi Yu, Weixi Guo
Published: 202510.1096/fj.202502184RR
Abstract
Lung adenocarcinoma (LUAD) metastasis is a major cause of patient mortality, with the key mechanism being the resistance of tumor cells to anoikis. HILPDA is associated with tumor progression, but its role and mechanism in anoikis in LUAD remain uncl…
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