FASEB journal : official publication of the Federation of American Societies for Experimental BiologyFerroptosisHumansColorectal NeoplasmsLymphoid Enhancer-Binding Factor 1Animals
LEF1 Suppresses Ferroptosis in Colorectal Cancer Cells by Targeted Promotion of SLC7A11 Transcription.
Yanan Chen, Zhennan Ma, Xiuqing Gong
Published: 202510.1096/fj.202502018R
Abstract
Ferroptosis has emerged as a promising therapeutic target for colorectal cancer (CRC) due to its ability to selectively eliminate cancer cells. By inducing ferroptosis, novel treatment strategies aim to overcome traditional challenges such as cancer…
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