FASEB journal : official publication of the Federation of American Societies for Experimental BiologyHumansPaclitaxelFemaleProtein Serine-Threonine KinasesUterine Cervical Neoplasms
CDK11 Promotes Paclitaxel Resistance in Cervical Cancer by Regulating LATS1-Mediated Hippo Signaling Pathway Through Phosphorylation of NF2.
Yan Zhang, Jingyan Lu, Minfang Qi, Xiaolu Zhang, Danmin Ou
Published: 202510.1096/fj.202501284RR
Abstract
Paclitaxel (PTX) is a first-line chemotherapeutic agent for cervical cancer, but resistance remains a major clinical challenge. This study investigates the role of cyclin-dependent kinase 11 (CDK11) in mediating PTX resistance and explores its underl…
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