FASEB journal : official publication of the Federation of American Societies for Experimental BiologyAnimalsReperfusion InjuryMiceLiverADAM Proteins
ADAM8 Destroys the Endothelial Barrier and Promotes Leukocyte Extravasation to Aggravate Hepatic Ischemia-Reperfusion Injury.
Ji Li, Wenwen Zhang, Yue Zhang, Huanqiu Liu
Published: 202510.1096/fj.202500697R
Abstract
Hepatic ischemia-reperfusion injury (HIRI) is a local aseptic inflammatory response driven by innate immunity, and it can severely damage liver function. ADAM8 belongs to the ADAM (a disintegrin and metalloprotease domain) family and has been shown t…
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