FASEB journal : official publication of the Federation of American Societies for Experimental BiologyAnimalsbeta CateninMiceReceptorNotch1
CXCR7 Facilitates the Migration and Proliferation of UCMSCs via β-Catenin/TCF4/MDM2 Signal Regulating Notch1 Ubiquitination to Ameliorate Pulmonary Fibrosis in ARDS.
Yan Cao, Zhirong Qian, Yuwei Yang, Jiahui Jin, David Y B Deng, Shuning Zhang, Lixin Xie, Kun Xiao
Published: 202510.1096/fj.202500609RR
Abstract
Umbilical cord mesenchymal stem cells (UCMSCs) hold therapeutic potential for acute respiratory distress syndrome (ARDS), but the role of atypical CXC chemokine receptor 7 (CXCR7) in their homing and reparative effects remains unclear. Using a lipopo…
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