Toxicological sciences : an official journal of the Society of Toxicology
Nrf2 contributes to the protective effect of iron overload on thioacetamide-induced chronic liver injury in rats.
Nanako Hamada, Yuri Ito, Hinata Niimi, Machi Atarashi, Mitsuru Kuwamura, Keiko Taguchi, Masayuki Yamamoto, Takeshi Izawa
Published: 202510.1093/toxsci/kfaf165
Abstract
Chronic liver disease (CLD) is a global health concern that progresses to liver cirrhosis and cancer. This progression can be partly replicated in rodents through experimental administration of thioacetamide (TAA). Hepatic iron accumulation is a rela…
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