Rheumatology (Oxford, England)
Exosomal miR-132-3p derived from M1 macrophages mediates diffuse alveolar hemorrhage in systemic lupus erythematosus.
Xun Chen, Jun Xie, Fuce Lu, Qiongyan Li, Guosheng Qiu, Chunfeng Liang
Published: 202510.1093/rheumatology/keaf600
Abstract
OBJECTIVE: This study examines how exosomal miR-132-3p from M1 macrophages contributes to the development of systemic lupus erythematosus (SLE)-associated DAH and the molecular mechanisms involved. METHODS: A pristane-induced murine model of SLE-DAH…
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