Rheumatology (Oxford, England)
Mechanical stress promotes synovial inflammation and osteoarthritis development via the NF-κB p52/IL-6 signaling pathway.
Yi Shen, Wei Sun, Yu Liu, Suxun Pan, Huanzhong Ji, Guangsen Zheng, Jiashun Wu
Published: 202510.1093/rheumatology/keaf553
Abstract
OBJECTIVES: Temporomandibular joint osteoarthritis (TMJOA) is a multifactorial degenerative disorder involving biomechanical and inflammatory processes. Yet, how mechanical stress causes synovial inflammation and cartilage degradation is unclear. Thi…
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