Rheumatology (Oxford, England)
Exploring the genetic interaction between ERAP1/ERAP2 and HLA-B*52:01 in Takayasu arteritis.
Desiré Casares-Marfil, Güher Saruhan-Direskeneli, Peter C Grayson, Enrico Tombetti, Lindi Jiang, Peter A Merkel, Vasculitis Clinical Research Consortium, Haner Direskeneli, Turkish Takayasu Study Group, Amr H Sawalha
Published: 202510.1093/rheumatology/keaf544
Abstract
OBJECTIVES: Takayasu arteritis is a rare vasculitis characterized by inflammation of large arteries. Given the robust genetic association with HLA-B*52:01, it was recently proposed to classify Takayasu arteritis within the spectrum of MHC-I-opathies.…
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