Reproduction (Cambridge, England)
Mild defects in follicular development and reproductive performance in the heterozygous Hfm1 female mouse.
Lavi Bhati, Adriana C Ene, Jessy Chen, Manqi Liang, Parinaz Kazemi, Jacinta H Martin, Rima Slim, Teruko Taketo
Published: 202610.1093/reprod/xaaf023
Abstract
HFM1 (Helicase For Meiosis 1) is an ATP-dependent DNA helicase expressed primarily in the germ cells and plays a conserved role in meiotic synapsis and recombination. Biallelic HFM1 mutations are responsible for female infertility and various forms o…
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