Protein & cell
Fibulin-7 in progenitor cells promotes adipose tissue fibrosis and disrupts metabolic homeostasis in obesity.
Hairong Yu, Fan Yang, Dandan Yan, Wei Chen, Lijun Yao, Hongli Chen, Siyu Lai, Jinyin Zha, Yi Sun, Yicen Zong, Jian Yu, Hong Zhang, Feng Jiang, Rong Zhang, Jian Zhang
Published: 202510.1093/procel/pwaf084
Abstract
Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance. Emerging evidence indicates that adipogenic stem and precursor cells (ASPCs) are a crucial…
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