Plant & cell physiology
Development of a Simple and Locus-Restricted DNA Methylation Editing System Using Direct Fusion of a Nickase-Type SpCas9 and DNA Methylation-Related Enzymes in Arabidopsis thaliana.
Shunya Hirata, Taisei Ozono, Kenshin Kawai, Chiyoko Machida, Kappei Kobayashi, Yoko Ikeda, Taisuke Nishimura, Hidetaka Kaya
Published: 202510.1093/pcp/pcaf162
Abstract
DNA methylation is an important epigenetic modification that regulates gene expression and supports genome stability. DNA methylation editing technology differs from conventional genome editing technology, which introduces mutations into genes, in th…
Preview only. Read the full abstract at the source