Neuro-oncology
Metabolic Profiling Defines Glioblastoma Subtypes with Distinct Prognoses and Therapeutic Vulnerabilities.
Fan Wu, Yi-Yun Yin, Di Wang, Chang-Qing Pan, You Zhai, Ming-Chen Yu, Zhi-Liang Wang, Wen-Hua Fan, Zheng Zhao, Guan-Zhang Li, Tao Jiang, Wei Zhang
Published: 202610.1093/neuonc/noaf294
Abstract
BACKGROUND: Glioblastoma (GBM) is a highly aggressive brain tumor with profound metabolic heterogeneity. However, a clinically actionable classification based on metabolic gene expression remains undefined. METHODS: We conducted a comprehensive multi…
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