Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Plasmacytoid dendritic cells modulate the production of mucosal IgA in IgA nephropathy.
Yusuke Fukao, Hitoshi Suzuki, Yoshihito Nihei, Yuko Makita, Toshiki Kano, Maiko Nakayama, Mingfeng Lee, Rina Kato, Masao Kihara, Yusuke Suzuki
Published: 202510.1093/ndt/gfaf216
Abstract
BACKGROUND AND HYPOTHESIS: Aberrantly glycosylated IgA plays a central role in the pathogenesis of Immunoglobulin A nephropathy (IgAN). The activation of Toll-like receptor (TLR) 9 has been shown to induce aberrant glycosylation of IgA via a prolifer…
Preview only. Read the full abstract at the source