Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
In situ assessment of glomerular C3/C5 convertases indicates ongoing complement activation in IgA nephropathy.
Augustin Obrecht, Marie-Sophie Meuleman, Jérôme Olagne, Anne Grunenwald, Sophie Chauvet, Lubka Roumenina, Véronique Frémeaux-Bacchi, Sophie Caillard, Anna Duval
Published: 202510.1093/ndt/gfaf200
Abstract
BACKGROUND AND HYPOTHESIS: The complement system contributes to the progression of IgA nephropathy (IgAN) and offers promising therapeutic targets currently under investigation. Identifying appropriate candidates for these treatments is now critical.…
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