TYGS and LPSN in 2025: a Global Core Biodata Resource for genome-based classification and nomenclature of prokaryotes within DSMZ Digital Diversity.

The List of Prokaryotic names with Standing in Nomenclature (LPSN, https://lpsn.dsmz.de/) is an authoritative, expert-curated resource on prokaryotic nomenclature. Its sister database, the Type (Strain) Genome Server (TYGS, https://tygs.dsmz.de/), is a high-throughput platform for genome-based taxonomy. Here we present updates to these two platforms. New tools include improved interoperability with other DSMZ Digital Diversity databases, as well as easy-to-use query and access functions, and more comprehensive submission forms. The database content has expanded considerably, particularly through the inclusion of thousands of cyanobacterial names and the compilation of the List of Recommended Names for bacteria of medical importance (LoRN). LPSN now contains over 59 000 taxon names, and over 23 500 genome sequences have been added to TYGS. LPSN and TYGS have been updated to incorporate and reflect changes to the official rules governing prokaryotic nomenclature, as ratified by the International Committee on Systematics of Prokaryotes (ICSP) in recent years.