Critical illness following kidney transplant: a case of xanthogranulomatous cholecystitis in a patient with multiple comorbidities.

We report the case of a 63-year-old female with significant comorbidities, including end-stage renal disease secondary to type 2 diabetes mellitus, who underwent a left kidney transplant. Post-operatively, she developed complications, including subcapsular hematoma, acute hypoxic respiratory distress, and bacteremia complicated by xanthogranulomatous cholecystitis. Despite aggressive medical interventions, her condition deteriorated, and comfort care measures were initiated. This case underscores the complexities and challenges in managing critically ill post-transplant patients and highlights the importance of a high index of suspicion of less common infections in this patient population.