The Journal of pharmacy and pharmacology
Effect of pigment epithelium-derived factor on prostaglandin E2 receptors (EP2/EP4) in glucocorticoid-induced osteoporosis in rats.
Zerrin Kutlu, Zekai Halici, Fatih Alper, Erdem Toktay, Adem Maman, Hamza Halici, Zafer Bayraktutan, Ahmet Yalcin
Published: 202510.1093/jpp/rgaf102
Abstract
OBJECTIVES: This study investigated the effects of pigment epithelium-derived factor (PEDF) on bone homeostasis in a glucocorticoid-induced osteoporosis (GIOP) rat model, focusing on prostaglandin E2 receptors EP2 and EP4. METHODS: Male Sprague-Dawle…
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