JNCI cancer spectrum
Tumor characteristics impact prognosis in dMMR/MSI-H localized colorectal cancer - a systematic review and meta-analysis.
Ida Kolukisa Saqi, Amalie Thomsen Nielsen, Michael Tvilling Madsen, Ismail Gögenur, Adile Orhan, Tobias Freyberg Justesen
Published: 202510.1093/jncics/pkaf114
Abstract
BACKGROUND: Deficient mismatch repair (dMMR) and microsatellite instability-high (MSI-H) tumors constitute approximately 15% of localized colorectal cancers (CRC). Prognostic biomarkers such as tumor-infiltrating lymphocytes (TILs) and BRAF and KRAS…
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