Journal of molecular cell biology
MEK1/2 inhibition prevents DENV and ZIKV infection via disrupting the cytoskeletal vimentin cage required for viral replication.
Yuhan Huang, Jiageng Lu, Shuzhi Cui, Shuangshuang Zhao, Shengming Sun, Yaming Jiu
Published: 202510.1093/jmcb/mjaf037
Abstract
Flaviviridae Dengue virus (DENV) and Zika virus (ZIKV) have posed significant threats to global public health in the past decades. Despite extensive study on therapeutic strategies against these viruses, effective treatment options are still lacking.…
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