Journal of leukocyte biology
Targeting CaMKIIδ Overcomes Therapy Resistance in Acute Myeloid Leukemia by Suppressing STAT3/CDK6/BCL-2 Survival Axis.
Zhaoxing Wu, Shuwen Zheng, Mengyuan Li, Xuzhao Zhang, Weiwei Zheng, Ping Wang, Qinyuan Gong, Xianghua Wu, Junxia Wu, Yun Liang, Rongzhen Xu
Published: 202510.1093/jleuko/qiaf184
Abstract
Relapse and therapy resistance remain major barriers to improving clinical outcomes in acute myeloid leukemia (AML), underscoring the need for actionable therapeutic targets. In this study, we identify calcium/calmodulin-dependent protein kinase II d…
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