Journal of leukocyte biology
Single-Cell Transcriptomic Analysis Reveals RNA-Binding Protein Dysregulation in Immune Checkpoint Inhibitor-Induced Colitis.
Haobei Ran, Lipan Zhang, Wentao Wang, Mingxi Xie, Fengqiao Wang, Lunjie Chen, Tingyu Pang, Aijia Chen, Jiayi Zhu, Hongke Cai
Published: 202510.1093/jleuko/qiaf181
Abstract
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by enhancing anti-tumor immunity, but their use is frequently complicated by immune-related adverse events (irAEs), particularly ICI-induced diarrhea and colitis. Growing evidence…
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