Journal of leukocyte biologyHepatitis A Virus Cellular Receptor 2HumansCytokine-Induced Killer CellsCytotoxicityImmunologic
Progenitor-predominant exhaustion in cytokine-induced killers reveals TIM-3 as a superior target for enhancing cytokine-induced killer cytotoxicity.
Jian Wang, Qin Wang, Jiahui Zhou, Li Zhou, Xiubao Ren, Feng Wei
Published: 202510.1093/jleuko/qiaf180
Abstract
Precursor exhausted and terminally exhausted T cells (Tpex and Tex) are associated with immune checkpoints; T-cell checkpoint blockade may improve patient survival. We assessed cytotoxic activity and PD-1/TIM-3 expressions of CD3+CD8+CD56+ T cells (N…
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