Journal of leukocyte biologyHumansSingle-Cell AnalysisFemaleTumor-Associated MacrophagesBreast Neoplasms
Single-cell analysis identifies inflammatory and tissue remodeling tumor-associated macrophages distinct from M1/M2 paradigm.
Eric López-Huerta, Diana P Portales-Pérez, Miguel E Martinez-Leija, Vianney Ortiz-Navarrete, Ezequiel M Fuentes-Pananá
Published: 202510.1093/jleuko/qiaf176
Abstract
Tumor-associated macrophages (TAMs) exert both pro- and antitumoral functions that influence cancer progression and patient prognosis. However, single-cell RNA sequencing (scRNA-seq) studies have revealed that TAM heterogeneity remains incompletely c…
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