Journal of immunology (Baltimore, Md. : 1950)
Aging changes the mechanism that underlies JAK2 modulation of neutrophil function.
Jacob W Feldmann, Matthew Kays, Farrah McGinnis, Emily Herron, Nurullah Sati, Clara Woods, Aminata P Coulibaly
Published: 202510.1093/jimmun/vkaf323
Abstract
Janus kinase 2 (JAK2) has been linked to various neutrophil functions, but the intracellular mechanisms underlying its modulation are unknown. Neutrophils are essential cells for host defense. Neutrophil effector functions include migration, neutroph…
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