Journal of immunology (Baltimore, Md. : 1950)
Fibroblast activation protein promotes natural killer cell invasion and tumor infiltration.
Rachael E Maynard, Allison A Fitzgerald, Emily F Marcisak, Apsra Nasir, Shira E Eisman, Eric Glasgow, Annabel J Lee, Nuan Wang, Sandra A Jablonski, Pieter Van Der Veken, Gray Pearson, Emily M Mace, Elana J Fertig, Marwa M Afifi, Louis M Weiner
Published: 202510.1093/jimmun/vkaf279
Abstract
Natural killer (NK) cells play essential roles in immunity, but their limited infiltration into solid tumors restricts their therapeutic potential. Here, we identify fibroblast activation protein (FAP), previously thought to be largely fibroblast-res…
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