Journal of immunology (Baltimore, Md. : 1950)
Ubiquitination of MHC class II molecules regulates B-cell development and response to antigens in mice.
Maxime Raymond, Renaud Balthazard, Astrid Zahn, Sasha Silva-Barrios, Akil Hammami, Abdelilah Majdoubi, Jun Seong Lee, Audrey Connolly, Antoine Sabourin, Tristan Galbas, Mohamed Abdelwafi Moulefera, Hideki Ogura, Satoshi Ishido, Mohammad Balood, Sébastien Talbot
Published: 202510.1093/jimmun/vkaf273
Abstract
Dendritic cells (DCs) and B lymphocytes produce major histocompatibility complex class II molecules (MHCIIs) in large amounts to maximize the display of peptides and fulfill their antigen-presentation functions. The surface expression of MHCIIs in th…
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