Journal of applied microbiology
Narrow-spectrum drug repurposing: targeting Gardnerella vaginalis biofilms associated with bacterial vaginosis.
William Johnston, Jamie Smith, Elisa Giammarini, Amy Campbell, Anthony J Slate, Ermando Canga, Marino Swanzy-Krah, Pranitha Murali, Mark Mason, Rebecca Metcalfe, Charlotte-Eve Short, Ryan Kean
Published: 202610.1093/jambio/lxag034
Abstract
AIM: Bacterial vaginosis (BV) is the most common vaginal disorder in women of reproductive age. Current therapies are limited by poor activity against biofilms and high recurrence rates (>50%), demonstrating that new antimicrobials are required. Drug…
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