The Journal of antimicrobial chemotherapyHIV IntegraseHumansHIV-1HIV InfectionsMutagenesis
First characterization of insertions in the HIV-1 integrase-coding region from people with HIV.
Nhat Quang Tu, Thomas Montrouge, Gladys Mbemba, Melissa Stampetta, Magali Bouvier-Alias, Véronique Avettand-Fenoël, Audrey Mirand, Coralie Pallier, Mary Anne Trabaud, Camille Tumiotto, Marc Wirden, Diane Descamps, Charlotte Charpentier, Eric Deprez, Vincent Parissi
Published: 202610.1093/jac/dkaf491
Abstract
OBJECTIVES: This study aimed to gain a better understanding of the role of insertional mutations in the integrase (IN)-coding sequence of 13 HIV-1-infected people. RESULTS: Here, we present the first documentation of amino acid insertion in the IN-co…
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