International immunology
KRAS mutations disrupt interactions between CD8+ T cells and antigen-presenting cells in the tumor microenvironment of biliary tract cancer.
Fumihiro Terasaki, Shogo Kumagai, Akito Fukuda, Yosuke Tanaka, Takuma Irie, Sachiko Ito, Mihoko Yamada, Shunsuke Onoe, Takashi Mizuno, Toshio Kokuryo, Shohei Koyama, Kennosuke Karube, Hiroyoshi Nishikawa, Tomoki Ebata
Published: 202510.1093/intimm/dxaf065
Abstract
Biliary tract cancer (BTC) exhibits a poor prognosis and limited responses to current therapeutic strategies. While surgical resection followed by adjuvant S-1 therapy is the standard curative treatment for BTC, long-term postoperative remission is h…
Preview only. Read the full abstract at the source