The Journal of infectious diseases
Microbiota, Mucus, and Modulators: CF Infection Pathogenesis in the CFTR Modulator Era.
Christina S Thornton, Drake C Bouzek, Lindsay J Caverly
Published: 202510.1093/infdis/jiaf626
Abstract
Cystic fibrosis (CF) lung disease is a result of defective CFTR-mediated ion transport, producing dehydrated mucus, impaired mucociliary clearance and an opportune environment for chronic airway infection. CF airway infections are polymicrobial airwa…
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