The Journal of infectious diseases
Manufacture of Clostridioides difficile spores for experimental infection of human volunteers.
Annefleur D O Hensen, Céline Harmanus, Christine Voorvelt, Anoecim R Geelen, Maryam El Hamdioui, Ed J Kuijper, Laura Pattacini, Pim Schipper, Inge M van Amerongen-Westra, Pauline Meij, M Y Eileen C Van der Stoep-Yap, Meta Roestenberg, Wiep Klaas Smits
Published: 202510.1093/infdis/jiaf612
Abstract
BACKGROUND: Infections with C. difficile remain a significant global healthcare problem for which novel (preventive) treatment strategies are urgently needed. Controlled human infection models (CHIMs) can contribute to a better understanding of the d…
Preview only. Read the full abstract at the source