The Journal of infectious diseases
Feasibility and Safety of Aerosolized Influenza Virus Challenge in Humans Using Two Modern Delivery Systems.
Nadine Rouphael, Ralph Tanios, Jessica Traenkner, Matthew D Pauly, Nishit Shetty, Meredith J Shephard, A J Campbell, Christelle Radi, Shamika Danzy, Jin Pan, Andrew P Catchpole, Alex Mann, Joshua F Detelich, Anice C Lowen, Linsey C Marr
Published: 202510.1093/infdis/jiaf603
Abstract
BACKGROUND: Controlled human infection models are widely used to study infectious diseases. Since the 1960s, these studies have primarily relied on intranasal inoculation, as earlier aerosol-based methods raised safety concerns and were largely aband…
Preview only. Read the full abstract at the source