ImmunoHorizonsAnimalsCD27 LigandTumor Necrosis Factor Receptor SuperfamilyMember 7Mice
Potential CD27-CD70 interaction within adoptive T cells does not affect tumor antigen-specific T-cell immunotherapy.
Eswara Rao Puppala, Mohammad A Alzubi, Habeebat Aderonke Mustapha, Sayon Basu, Chang-Yong Choi, Long Wu, Xiaoxuan Fan, Xuefang Cao
Published: 202610.1093/immhor/vlaf086
Abstract
The CD27-CD70 pathway regulates T-cell activity either positively or negatively depending on the context of immune response. Typically, CD27 is known as a co-stimulatory receptor expressed on T cells while CD70 is the ligand expressed on antigen-pres…
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