Inflammatory bowel diseasesInterleukin-15Th17 CellsHumansAnimalsMice
IL-15 Promotes Inflammatory Th17 Cells in the Intestine.
Guoqing Hou, Allen Lee, Jonathan L Golob, Helmut Grasberger, Elliott Berinstein, Benjamin J Swanson, Shreenath R Bishu, Mohamed El Zataari, Valerie Khaykin, Jeff A Berinstein, Christopher Fry, Jean Nemzek, Nobuhiko Kamada, John Kao, Shrinivas Bishu
Published: 202510.1093/ibd/izaf222
Abstract
Ulcerative colitis (UC) is a chronic gastrointestinal condition with high morbidity. Modern therapies have revolutionized the care of UC, but 10% to 25% of patients do not respond to treatments and many progress to surgery. Thus, developing new treat…
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