Inflammatory bowel diseasesHumansInflammatory Bowel DiseasesResearch DesignClinical Trials as TopicBiomarkers
How Should an IBD Prevention Trial Be Designed?
Rogier L Goetgebuer, Ryan C Ungaro, Brian G Feagan, Vipul Jairath, Jean-Frédéric Colombel, Geert R A M D'Haens
Published: 202510.1093/ibd/izaf212
Abstract
BACKGROUND: Advances in understanding disease pathogenesis have revealed a preclinical phase of inflammatory bowel disease (IBD), offering a potential window for preventive measures. There is growing interest in trials to prevent IBD in at-risk indiv…
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