Human reproduction (Oxford, England)
Ovarian function compromise in pediatric beta-thalassemia major: a consequence of iron overload-induced mitochondrial and fibrotic damage.
Xiaoping Liu, Peigen Chen, Yongfang Li, Weie Zhao, Xiaoke Zheng, Peng Sun, Yingchun Guo, Cong Fang, Xiaoyan Liang, Jingjie Li
Published: 202610.1093/humrep/deaf250
Abstract
STUDY QUESTION: How does iron overload affect ovarian function in pediatric patients with transfusion-dependent beta-thalassemia major? SUMMARY ANSWER: Iron overload in pediatric patients with beta-thalassemia major is strongly associated with decrea…
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